Viscosine was isolated from Dodonaea viscosa, which showed significant\r\nlipoxygenase inhibitory activity (IC50: value 39 �± 0.17). Molecular docking\r\nsimulations were conducted to explore molecular binding mode, and to help\r\nelucidate molecular mechanism behind its significant inhibitory activity.\r\nMolecular interactions of viscosine with catalytic triad (His523, His518, Ile875)\r\ninside active site of lipoxygenase via hydrogen bonding, seems to be the major\r\nfactor involved in its significant lipoxygenase inhibitory activity.
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